Injectable liquid can be filled and rubber-stoppered into vials using the Two Head Vial Filling Machine. The machine is finished in attractive Matt-finished stainless steel construction. The basic unit includes a turntable/unscramble, an SS Stat conveyor belt, very precise and efficient SS 316 syringes, non-toxic synthetic rubber tubing, and an easy-to-reach compact panel. The risk of contamination is decreased by the minimal distance between the filling and stoppering units. The machines are made to operate under laminar flow protection and in a sterile environment.
For small to medium-sized sterile filling applications, Adinath International’s Two Head Liquid Vial Filling Machine with Rubber Stoppering is a practical and affordable option. This equipment uses volumetric piston pumps to fill 2 ml to 100 ml vials with an accuracy of ±1%. It guarantees seamless vial transfer from filling to stoppering by integrating a synchronised conveyor and star wheel holding mechanism. High-quality SS316 contact parts, nitrogen flushing assistance, and the “No Vial, No Filling” function guarantee contamination-free operation that satisfies cGMP and CE requirements. It is ideal for pharmaceutical and R&D labs due to its vibration-free design and simple operation.
This type strikes a balance between performance and cost while guaranteeing accurate and secure liquid filling, with a production speed of 30–50 vials per minute and compatibility with stopper sizes 13mm to 32mm (full & half).
This bottom-up filling technique handles both low- and high-viscosity liquids efficiently, with independent head operation allowing continuous production even if one head encounters an issue.
The incoming dry vials (sterilized and siliconized) are fed through the unscrambler and suitably guided on the moving Delrin slat conveyor belt at the required speed of the correct placement below filling unit.
The filling unit consists of Filling Head, Syringes & Nozzles; Syringes & Nozzles are made of AISI SS 316L materials. A Star Wheel is provided which holds the vial during filling operation. A sensor is provided for ”No Vial-No Filling” operation. Syringes are mounted on eccentric block and driving through bottom main gear box. Volume can be increase & decrease by increasing or decreasing stroke length of piston as per filling size. Syringes is having non return valve for sucking and delivering situation to avoid volume variation. Liquid reaches to filling nozzles through silicon transparent pipe. Nozzles having up & down movement with help of cam mechanism, and it come down when vial hold by starwheel for filling operation and starts filling when it starts to move up and after completion of filling operation, starwheel delivers two vials together on conveyor for rubber stoppering operation.
Stoppering unit consist of Star wheel, Vibrator unit and Bowl. The sterilized and siliconized rubber stoppers stored in the vibrator bowl moves vertically to the rubber stopper chute. The vial is hold firmly by starwheel, which will be in continuous rotary motion and vial which is coming from filling unit get in to starwheel and move in rotary direction along with starwheel, during movement it picks up the rubber stopper from the exit end of the chute and rubber stopper pressed by fix single pressing roller, which is spring loaded. Then vial further move on conveyor and collected on out feed starwheel for next sealing operation.
Model | ALVF-40 |
Filling Heads | Two |
Production Rate | Up to 40 Vials/Minute |
Vial Diameter | 15mm to 70mm |
Vial Height | 25mm to 140mm |
Filling Precision | ±1% |
Power Required | 1 H.P. |
Electrical Characteristics | 440 Volts, 3 Phase, 50 Hertz |
Overall Dimension | 2050mm (L) x 850mm (W) x 1700mm (H) |
* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.
The standard model (ALVF-40) delivers an output of 30 to 50 vials per minute (approximately 1,800–3,000 vials per hour), depending on vial size and fill volume. Higher-capacity variants like ALVF-80, ALVF-120, or ALVF-250 are also available for faster production needs. Speed can be easily adjusted using the variable AC frequency drive.
The machine handles round glass vials with diameters from 15 mm to 70 mm and heights from 25 mm to 140 mm. It supports fill volumes from 2 ml to 250 ml. Stopper sizes range from 13 mm to 32 mm (full or half stoppering). Change parts are available for quick changeover between different vial formats.
The machine provides excellent filling accuracy of ±0.5% to ±1%, thanks to precision SS 316L syringes, piston pumps (or optional peristaltic pumps), and non-return valves. This level of precision ensures consistent dosing for sterile injectables, vaccines, antibiotics, and biologics while meeting stringent cGMP and regulatory requirements.
The machine is equipped with a sensor-based “No Vial – No Filling” and “No Vial – Machine Stop” system. If a vial is missing at the filling station, the machine automatically stops filling (and optionally the entire machine) to prevent liquid spillage, product wastage, and contamination. This feature enhances safety and reduces operational costs.
Yes. It is fully cGMP and CE compliant, with all product contact parts made of SS 316L (syringes, nozzles, and piping) and the framework in SS 304. The compact design allows operation under laminar airflow. It supports nitrogen flushing and offers easy validation with IQ/OQ documentation, making it perfect for aseptic filling of parenteral products in controlled sterile environments.
Key features include synchronized star wheel and conveyor, cam-operated nozzle movement, vibration-free operation, digital vial counter, overload protection, and minimal distance between filling and stoppering stations for better sterility. Optional accessories include:
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Connect with our engineering team to discuss your specific production requirements. We provide customized, cGMP-compliant machinery solutions designed to optimize your manufacturing facility and maximize output.
Adinath International manufactures high-precision vial powder filling machines and complete packaging lines, providing reliable, hygienic, and efficient solutions for global pharmaceutical industries.
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