

Vial Powder Filling & Plugging Machine was designed to facilitate the filling of injectable glass vials with liquid. Conveyor belts, turntables, pre-gassing, filling, and post-gassing components make up the machine’s main components. The 316L quality stainless steel used to make this plugging and capping machine satisfies GMP requirements and guarantees the highest long-term return on investment. Easy access is made possible by the small panel and synthetic rubber tubes.
The self-picking roller-based rubber stoppering technology of the Automatic High Speed Injectable Dry Powder Filling with Rubber Stoppering Machine is entirely mechanical. This machine can tolerate extended working hours and has a very robust build. A vacuum and air pressure-based powder wheel with a manual fill weight adjustment is used for filling. From monolithic mechanical machines to our cutting-edge servo-driven centralised piston adjustment aspetic vial powder filling machine, which is intended to fill microdoses of sterile powder into glass vials and seal them with rubber stoppers, we have developed a variety of aseptic (sterile) powder filling and rubber stoppering machines.
We are a top producer of Automatic Dry Injectable Powder Filling Machine, Vial Filler, High Speed Injectable Powder Filling Machine, Automatic Vial Powder Filling Machine, Dry Syrup Powder Filling Machine, High Speed Dry Syrup Powder Filling Machine, Vial Filling and Stoppering Machine, Vial Filling and Plugging Machine, Vial Dry Powder Filling Machine, Powder Injection Vial Filling Machine, Sterile Powder Filler Rubber Stoppering Machine, etc. automated filling systems, sterile and aseptic processing, and pharmaceutical manufacturing.
The sterilized powder is stored in powder hopper is agitated by pair of mechanical agitators for maintaining consistency and uniform bulk density. The powder wheel having eight ports rotates at the pre determined speed below the powder hopper with practically no clearance. Powder wheel consist of Piston in each port and behind the powder wheel vacuum plate is provided there is no clearance between powder wheel and vacuum plate due to back spring pressure. Precise volume of powder is sucked in to the port of powder wheel during vacuum according to the piston length different fill size can be achieved. The excess powder is doctored off by a doctor blade. Doctor blades can be adjusted from outside also without removing powder hopper. When powder wheel indexes further and remain in the port due to the vacuum till it reaches just vertically above the container. The time dose of Compressed air (Nitrogen Gas), sterilized low pressure air sequentially flushes out powder from the port of powder wheel in to the container one by one. The filled containers are immediately separated on the conveyor by vial separator and moves further for stoppering operation. (Different grooves separator can be used which depends on the container diameter or multiple dosing systems). The sterilized, siliconised, rubber stoppers stored in the vibrator bowl moves to vibratory bowl and stacked vertically in the rubber stopper chute. The container is hold firmly between pair or timing belt to pickup rubber stopper from exit end of the chute. Further the container is passed between two pressing roller for tight fit fixing of rubber stopper.
Models | APF 12S | APF 12D |
Production Output | Up to 100 vials/minute | Up to 200 vials/minute |
Fill Volume | 50 mg. to 10grams | 50 mg. to 10 grams |
Vial Size | 5ml to 250ml | 5ml to 250ml |
Filling Accuracy | ± 2 – 3% in single dosing depending upon consistency and uniformity of bulk density of Injectable Powder | ± 2 – 3% in single dosing depending upon consistency and uniformity of bulk density of Injectable Powder |
Power Load | 3.5 H. P. | 4.5 H. P. |
Overall Dimension | 2600mm (L) X 1100mm (W) X 1800mm (H) approx. | 3000mm (L) X 1100mm (W) X 1800mm (H) approx. |
Net Weight | 500 kgs. approx. | 700 kgs. approx. |
Gross Weight | 750 kgs. approx. | 950 kgs. approx. |
* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.
A Vial Powder Filling & Plugging Machine is a compact monoblock system designed for high-speed, aseptic filling of sterile injectable powders into glass vials followed by automatic rubber stoppering (plugging). It uses a vacuum-based powder wheel system and is ideal for antibiotics and other dry powder injections in pharmaceutical manufacturing.
The machine is available in two main models:
It supports vial sizes from 5 ml to 250 ml and fill volumes from 50 mg to 10 grams per vial.
The machine offers a filling accuracy of ±2% to ±3% (depending on powder bulk density and uniformity). Accuracy is achieved through precise piston depth adjustment in the powder wheel ports and consistent vacuum + compressed air/nitrogen dosing.
The machine uses an eight-port powder wheel with vacuum suction. Sterile powder from an agitated hopper is drawn into the ports. Excess powder is removed by a doctor blade for uniform density. Compressed air (or nitrogen) then flushes the exact dose into the vial. This is followed by immediate rubber stoppering to maintain sterility.
Key anti-wastage features include:
United States | Canada | Mexico | Brazil | Argentina | Chile | Colombia | Peru | Germany | United Kingdom | France | Italy | Spain | Netherlands | Belgium | Switzerland | Sweden | Austria | Denmark | Norway | Poland | Finland | Czech Republic | Hungary | Portugal | Ireland | Greece | Slovakia | Romania | Bulgaria | China | Japan | India | South Korea | Indonesia | Vietnam | Thailand | Malaysia | Philippines | Singapore | Bangladesh | Pakistan | Saudi Arabia | United Arab Emirates | Israel | Turkey | Iran | Qatar | Kuwait | South Africa | Nigeria | Egypt | Algeria | Morocco | Kenya | Ghana | Tunisia | Australia | New Zealand | Russia | Ukraine | Belarus | Kazakhstan | Taiwan | Hong Kong | South Sudan | Uzbekistan | Oman | Jordan | Bahrain | Sri Lanka | Myanmar | Lebanon | Mongolia | Ethiopia | Libya | Angola | Zambia | Zimbabwe | Mozambique | Ivory Coast | Senegal | Uganda | Tanzania | Botswana | Ecuador | Venezuela | Bolivia | Paraguay | Uruguay | Trinidad and Tobago | Panama | Guatemala | Costa Rica | Honduras | El Salvador | Nicaragua | Dominican Republic | Haiti | Cuba
Connect with our engineering team to discuss your specific production requirements. We provide customized, cGMP-compliant machinery solutions designed to optimize your manufacturing facility and maximize output.
©Adinath International | Theme Developed By Pharma Machinery Manufacturer
WhatsApp us