

In the fast-paced pharmaceutical manufacturing sector, precision, sterility, and efficiency are non-negotiable. The ADINATH Eight Head Vial Filling Machine stands out as a robust, high-performance automatic vial filling and stoppering system designed to meet the stringent demands of injectable drug production. Engineered with advanced technology and premium materials, this machine ensures consistent output, minimal contamination risk, and full compliance with GMP standards. Whether you are a pharmaceutical manufacturer, contract development and manufacturing organization (CDMO), or biotech company, the ADINATH eight-head vial filler delivers reliable performance that professionals trust.
The ADINATH Eight Head Vial Filling Machine features a heavy-duty construction with attractive matt-finished stainless steel (SS) surfaces that are easy to clean and resistant to corrosion. It incorporates one or both side turntables, a durable S.S. slat conveyor belt, and a specialized co-eccentric simultaneous gassing and filling system. Sterilized dry vials are gently fed through an unscrambler and precisely positioned on the moving Delrin slat conveyor belt at the optimal speed for accurate placement beneath the filling heads. The machine’s core components include high-quality turntables, an SS slat conveyor, ultra-precise SS 316L syringes, non-toxic synthetic rubber tubing, and a user-friendly compact control panel. Its compact footprint and ergonomic design make it ideal for integration into existing sterile production lines operating under laminar airflow protection.
Vial feeding is fully automated and gentle on delicate glass containers. Sterilized and siliconized vials are loaded via a reliable unscrambler onto the conveyor belt. A star wheel mechanism ensures accurate and vibration-free positioning under the eight filling heads, maintaining smooth, high-speed operation without jamming or breakage. At the heart of the machine are eight independent filling heads powered by high-accuracy piston or peristaltic pumps. Operators can easily adjust stroke lengths to fill volumes ranging from 2 ml to 250 ml with exceptional accuracy. Nitrogen purging before and during filling displaces oxygen, preserving product integrity and extending shelf life for sensitive injectables. The servo motor drive combined with PLC control and intuitive touch screen HMI allows real-time parameter adjustments, recipe management, and seamless operation by a single technician.
One of the machine’s key advantages is the minimal distance between the filling and stoppering stations. This design significantly reduces the risk of airborne contamination. Rubber stoppers (up to 20 mm diameter) are automatically placed with ±1% accuracy using a vacuum bung hold disc and pneumatic pressing system. Vacuum air pressure ensures secure, consistent stopper insertion without damaging the vials or compromising sterility. Filled and stoppered vials are smoothly transferred to an outfeed turntable for downstream processes such as capping, labeling, or inspection. The entire system is driven by a high-quality imported gear motor, delivering vibration-free, quiet, and reliable performance even during extended production runs. Typical output capacities make this machine suitable for medium to large-scale pharmaceutical production.
With decades of expertise in pharmaceutical machinery, ADINATH machines are built for longevity, ease of maintenance, and regulatory compliance. The combination of servo-driven precision, PLC automation, nitrogen gassing, and robust stainless-steel construction ensures maximum uptime and product safety. Users consistently report reduced rejection rates, lower operational costs, and simplified validation processes. For pharmaceutical companies seeking a dependable eight head vial filling machine, automatic vial filler with stoppering, or a complete sterile liquid filling line, the ADINATH solution offers proven expertise, engineering excellence, and trustworthy performance that meets today’s demanding industry standards.
The incoming dry vials (sterilized and siliconized) are fed through the unscrambler and suitably guided on the moving Delrin slat conveyor belt at the required speed of the correct placement below filling unit.
The filling unit consists of Filling Head, Syringes & Nozzles; Syringes & Nozzles are made of AISI SS 316L materials. A Star Wheel is provided which holds the vial during filling operation. A sensor is provided for ”No Vial-No Filling” operation. Syringes are mounted on eccentric block and driving through bottom main gear box. Volume can be increase & decrease by increasing or decreasing stroke length of piston as per filling size. Syringes is having non return valve for sucking and delivering situation to avoid volume variation. Liquid reaches to filling nozzles through silicon transparent pipe. Nozzles having up & down movement with help of cam mechanism, and it come down when vial hold by starwheel for filling operation and starts filling when it starts to move up and after completion of filling operation, starwheel delivers two vials together on conveyor for rubber stoppering operation.
Stoppering unit consist of Star wheel, Vibrator unit and Bowl. The sterilized and siliconized rubber stoppers stored in the vibrator bowl moves vertically to the rubber stopper chute. The vial is hold firmly by starwheel, which will be in continuous rotary motion and vial which is coming from filling unit get in to starwheel and move in rotary direction along with starwheel, during movement it picks up the rubber stopper from the exit end of the chute and rubber stopper pressed by fix single pressing roller, which is spring loaded. Then vial further move on conveyor and collected on out feed starwheel for next sealing operation.
Model | ALVF-120 |
Filling Heads | Eight |
Production Rate | Up to 150 Vials/Minute |
Vial Diameter | 15mm to 70mm |
Vial Height | 25mm to 140mm |
Filling Precision | ±1% |
Power Required | 2 H.P. |
Electrical Characteristics | 440 Volts, 3 Phase, 50 Hertz |
Overall Dimension | 3000mm (L) x 945mm (W) x 1700mm (H) |
* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.
The production speed typically ranges from 80 to 240 vials per minute. The exact output depends on several factors, including the fill volume, the diameter of the vial neck, and the viscosity of the liquid being processed. For most standard 5ml to 10ml vials, you can expect a stable high-speed performance suitable for medium-to-large scale batches.
Yes. While the machine is optimized for high-speed consistency, it is designed with flexibility in mind.By usingchange-over parts, you can adjust the machine to handle various vial diameters and heights. Fill volumes are typically adjustable via a PLC (Programmable Logic Controller) or manual syringe settings, depending on whether the model uses a piston or a peristaltic pump system.
Precision is a hallmark of this equipment. Most modern eight-head fillers offer a filling accuracy of ±0.5% to 1%. Each of the eight heads can be individually calibrated to ensure uniformity across the entire conveyor row, which is critical for maintaining dosage consistency and reducing product wastage.
Absolutely. Our Eight Head Vial Filling Machines are manufactured to meet cGMP (current Good Manufacturing Practice) standards. All contact parts are made from SS 316L to prevent corrosion and contamination, while non-contact parts are made from SS 304. The design also supports CIP (Clean-in-Place) and SIP (Steam-in-Place) protocols for sterile environments.
The machine is equipped with a “No Vial – No Fill” sensor system. This ensures that if a vial is missing from the sequence or tipped over, the corresponding filling head will not discharge the product. This prevents machinery contamination, saves expensive liquid product, and reduces the need for manual cleaning during a production run.
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Connect with our engineering team to discuss your specific production requirements. We provide customized, cGMP-compliant machinery solutions designed to optimize your manufacturing facility and maximize output.
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Connect with our engineering team to discuss your specific production requirements. We provide customized, cGMP-compliant machinery solutions designed to optimize your manufacturing facility and maximize output.
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