Powder Filling Machine for Glass Vials Bottles

The machine uses a vacuum-based powder wheel system (typically with an eight-port wheel). Sterile powder from an agitated hopper is drawn into the ports by vacuum according to the piston depth. Excess powder is removed by a doctor blade for uniform density. Compressed air (or nitrogen) then flushes the precise dose into the vial. Filled vials move to the built-in vibrator-type rubber stoppering station, where stoppers are pressed in place. A “No Vial, No Filling” system prevents wastage.

The machine handles round glass vials from 5 ml to 250 ml. The fill volume ranges from 50 mg to 10 grams per vial (depending on the model and powder density). It supports single or multiple dosing and is suitable for both single-track (up to 100 vials/min) and double-track (up to 200 vials/min) configurations. Change parts are available for different vial and dose ranges.

Filling accuracy is typically ±2% (or better with servo-controlled options), depending on the powder’s uniform bulk density.

• Single-track model (APF 12S): Up to 100 vials per minute.
• Double-track model (APF 12D): Up to 200 vials per minute (approx. 12,000 vials/hour). Higher outputs are achievable with optimized settings and consistent powder flow. A digital counter tracks production output.

Yes. It is a cGMP-compliant model designed for aseptic processing of sterile powders. All powder-contact parts are made of SS316/SS316L (FDA-approved materials) and are easily removable for autoclaving/sterilization. It features a built-in rubber stoppering unit, safety systems, and optional inbuilt Class 100 laminar airflow, making it ideal for antibiotics and other injectable powders in controlled sterile areas.

Important features include the “No Vial, No Filling” system, which prevents filling when no vial is present, a safety clutch to avoid vial breakage, individual drives for filling and stoppering, variable AC frequency drive for speed control, and overload protection. Agitators in the hopper maintain consistent powder flow and uniform density. All contact parts are designed for easy cleaning and sterilization.

Yes, the machine is highly customizable. Options include servo motors, in-process weight checking with automatic rejection, multiple dosing systems, split-filling for different powders, inbuilt laminar airflow, and different powder wheel configurations (single/double track, single/double powder wheel). It can be integrated into a complete vial washing–sterilizing–filling–capping line. We also provide IQ/OQ documentation and change parts for various vial sizes and doses.