

The Onion Skin Ampoule Filler is a high-performance solution designed for precise filling and sealing of glass ampoules. Widely used across the pharmaceutical, biotech, cosmetic, veterinary, and chemical industries, this machine ensures superior product safety and efficiency. We manufacture both standard and custom Onion Skin Ampoule Filling and Sealing Machines tailored to meet specific client requirements. Built on the reliable slant travel principle, the machine easily accommodates a wide range of ampoule neck dimensions, thicknesses, and ovality. It supports ampoules with diameters of 6 to 15 mm and lengths of 55 to 150 mm, including biological indicator ampoules. Operating with minimal human intervention, the Onion Skin Ampoule Filling Machine significantly reduces contamination risks during the filling and sealing process. It delivers high output of up to 200 ampoules per minute, making it ideal for medium to large-scale production.
The Ampoule Filling and Sealing Machine is built on a robust square pipe frame made of premium stainless steel, ensuring long-lasting durability and corrosion resistance. The entire machine is fully covered with stainless steel panels featuring an elegant matt finish, giving it a professional look while maintaining high hygiene standards essential for pharmaceutical production. For easy cleaning and maintenance, the machine features a large opening area at the bottom, allowing thorough access to internal components. To enhance operator convenience and safety, the electrical control panel is designed in a user-friendly pendant style, positioned away from the main machine body.
The sterilized ampoule tray directly loaded in to slant hopper of the unit. The Synchronized star wheel delivers ampoules, one by one on moving eccentric ampoule rack in single/double/four/six/eight. During the movement of ampoule machine perform below mentioned operations:
At the end duly filled and sealed ampoules get collected automatically onto collection tray of the machine. Ampoules now can be collected for further inspection and/or sticker labeling operations.
Model | OFS-1 | OFS-2 | OFS-4 | OFS-8 |
| Filling Heads | Single | Two | Four | Eight |
Ampoule Size Range | 1ml to 30ml | 1ml to 30ml | 1ml to 10ml | 1ml to 20ml |
| Filling Speed | Up to 25 ampoules per minute | Up to 50 ampoules per minute | Up to 100 ampoules per minute | Up to 200 ampoules per minute |
Power Requirement | 0.5 H.P. | 1.0 H.P. | 1.0 H.P. | 2.0 H.P. |
| Machine Dimensions | 915mm (L) x 610mm (W) x 965mm (H) approx. | 915mm (L) x 760mm (W) x 965mm (H) approx. | 1200mm (L) x 1070mm (W) x 965mm (H) approx. | 2200mm (L) x 1400mm (W) x 1100mm (H) approx. |
* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.
The Onion Skin Ampoule Filler (Models OFS-1, OFS-2, OFS-4 & OFS-8) is a fully automatic, compact monoblock cGMP-compliant machine specially designed to fill and hermetically seal thin-walled onion skin ampoules (also called crushable glass tubes or biological indicator tubes). It uses volumetric piston pumps for precise filling and LPG + Oxygen flame sealing. The slant travelling mechanism with ampoule neck centering handles variations in neck dimensions, thickness (0.3–0.8 mm), and ovality. It is ideal for packaging agro-insecticides, veterinary medicines, cosmetics, chemicals, and biological indicators in pharmaceutical, biotech, cosmetic, veterinary, and chemical industries.
Production capacity varies by model:
This gives a maximum output of up to 12,000 ampoules per hour. Speed is adjustable via variable frequency drive, and actual output depends on ampoule size, fill volume, and product viscosity. It is suitable for both medium and high-volume production of thin onion skin tubes.
The machine is specially engineered for small, thin onion skin ampoules with diameter 6–15 mm and length 55–150 mm (minimum 7 mm diameter × 55 mm height). It supports:
It delivers ±1% filling accuracy and easily accommodates variations in glass thickness and ovality thanks to the slant travel design and neck centering system.
Yes. It features pre-, during, and post-nitrogen flushing with ampoule neck centering to remove oxygen, prevent oxidation, and maintain product stability and sterility. Additional sterile features include a “No Ampoule – No Filling” system to eliminate wastage, a pre-heating station, and precise flame sealing. All product contact parts are made of SS 316L, and the machine is fully cGMP compliant, making it suitable for sensitive liquids, biological indicators, and contamination-free processing.
Key features include:
Benefits: Gentle handling to prevent breakage of thin glass, high-speed production, excellent dosing precision, superior sterility, reduced product wastage, hermetic sealing for longer shelf life, and no human touch during operation. Optional PLC/HMI, servo filling, and laminar airflow are also available.
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Connect with our engineering team to discuss your specific production requirements. We provide customized, cGMP-compliant machinery solutions designed to optimize your manufacturing facility and maximize output.
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