Dry Injection Filling Machine

These machines typically use vacuum or servo-controlled powder dosing systems. Vials are automatically fed, filled with a precise dose of dry powder under controlled conditions (often under laminar airflow), stoppered, and then capped or sealed. Advanced models feature synchronized star wheels, powder wheels, and “no vial – no fill” safety systems to ensure accuracy and prevent wastage.

Modern dry injection filling machines achieve filling accuracy of ±1% to ±2%, depending on powder characteristics, fill weight, and machine configuration. Servo-driven and vacuum-based systems offer excellent repeatability, which is critical for potent or low-dose injectable powders.

The machine can process free-flowing and semi-free-flowing dry powders. It is suitable for a wide range of vial sizes (commonly 2 ml to 30 ml or more, depending on the model) and can be equipped with change parts for different neck diameters and fill volumes.

Yes. These machines are designed for aseptic processing. They are typically constructed with SS316L contact parts, support operation under Class 100 laminar airflow, and often include features such as nitrogen flushing, rubber stoppering, and easy sterilization to maintain sterility and meet USFDA, WHO, and cGMP guidelines.

Output varies by model and configuration. Semi-automatic machines may handle lower volumes, while fully automatic rotary systems can achieve speeds from 60 to 300+ vials per minute, depending on fill volume, powder type, and vial size.

Key benefits include high dosing accuracy, reduced product wastage, excellent sterility control, consistent fill weights, lower labor dependency, and full compliance with pharmaceutical regulatory standards. Integrated filling, stoppering, and capping options further improve line efficiency.

Contact parts are designed for quick dismantling and are usually autoclave-compatible. Many models support CIP/SIP concepts or easy manual cleaning. Change parts for different vial sizes or fill volumes allow relatively fast changeovers, minimizing downtime between batches.

Yes. These machines can be seamlessly integrated with vial washing machines, sterilization tunnels, rubber stoppering units, capping machines, labeling systems, and inspection equipment to create a complete sterile injectable powder filling line.

Standard safety features include “No Vial – No Fill,” vial breakage detection, overload protection, and emergency stops. Advanced models offer PLC controls with HMI, recipe management, audit trails, and optional 100% weight checking or rejection systems to ensure only correctly filled vials proceed further.