Adinath Machine stands as a leading manufacturer of the Dry Powder Filling Bunging Machine, delivering advanced, reliable solutions for pharmaceutical injectable powder packaging. With deep industry experience and a strong focus on precision engineering, the company designs equipment that meets the exacting demands of modern sterile manufacturing. This high-speed machine operates entirely through a robust mechanical system and features a self-picking roller-based rubber stoppering (bunging) mechanism. The combination of accurate powder dosing and automatic bung placement in a single integrated platform ensures efficient, contamination-controlled production of dry powder injectables.
The filling process relies on a proven vacuum and air pressure-based powder wheel system. This technology allows operators to achieve precise dosing while enabling convenient manual adjustment of fill weight according to product requirements. Specially engineered for round glass vials, the machine is available in configurations that deliver production speeds of up to 120 or 250 vials per minute, depending on the model and application. The APF series models are constructed with a complete stainless-steel finish, including the structural frame, and are fully compliant with current Good Manufacturing Practice (cGMP) standards. These design choices reflect Adinath’s commitment to quality, durability, and regulatory adherence.
One of the primary advantages of this automatic vial filling machine is its high filling accuracy combined with consistent performance. The system minimizes powder wastage through controlled dosing and safety interlocks, while handling high volumes of vials per hour with minimal operator intervention. Easy operation further reduces training requirements and supports smooth day-to-day production. Customers can select from various combinations of filling heads and powder wheels to achieve higher speeds or accommodate larger fill volumes, providing the flexibility needed for different product ranges and batch sizes.
All product-contact parts—those that touch the vial, powder, or rubber stopper—as well as components exposed to the atmosphere, are manufactured from stainless steel SS316. This material selection ensures excellent corrosion resistance, ease of cleaning and sterilization, and long-term compliance with stringent pharmaceutical quality standards. The result is a durable machine that delivers reliable performance with minimal downtime and reduced maintenance needs, making it a valuable asset in any sterile manufacturing facility.
Powder filling is a critical process across multiple industries, particularly pharmaceuticals, where dry powders must be accurately dosed into vials or bottles under controlled conditions. Manual methods or outdated equipment often lead to inconsistent fills, product loss, and increased contamination risks. Modern Dry Powder Filling Bunging Machines solve these challenges by combining precision dosing with automatic rubber stoppering in a compact, hygienic design. Pharmaceutical, clinical, and related manufacturing facilities rely on these systems to maintain product integrity, meet regulatory requirements, and achieve efficient high-volume output. By integrating proven vacuum-pressure technology, mechanical reliability, cGMP-compliant construction, and user-friendly operation, Adinath’s Dry Powder Filling Bunging Machine offers pharmaceutical manufacturers a trusted solution for accurate, efficient, and sterile powder filling operations.
The sterilized powder is stored in powder hopper is agitated by pair of mechanical agitators for maintaining consistency and uniform bulk density. The powder wheel having twelve ports which rotates at pre-determined speed below the powder hopper with practically no clearance. Powder wheel consist of Piston in each port and behind the powder wheel vacuum plate is provided. There is no clearance between powder wheel and vacuum plate due to back spring pressure. Precise volume of powder is sucked into the port of powder wheel during vacuum; according to the piston length different fill size can be achieved. The excess powder is doctored off by a doctor blade. Doctor blades can be adjusted from outside also without removing powder hopper. When powder wheel indexes further and remain in the port due to the vacuum till it reaches just vertically above the container. The time dose of Compressed air (Nitrogen Gas), sterilized low pressure air sequentially flushes out powder from the port of powder wheel in to the container one by one.
The filled containers are immediately separated on the conveyor by vial separator and moves further for stoppering operation. The sterilized, siliconised, rubber stoppers stored in the vibrator bowl moves to vibratory bowl and stacked vertically in the rubber stopper chute. The container is hold firmly between pair or timing belt to pickup rubber stopper from exit end of the chute. Further container is passed between two pressing roller for tight fit fixing of rubber stoppers.
Models | APF 12S | APF 12D |
Production Output | Up to 100 vials/minute | Up to 200 vials/minute |
Fill Volume | 50 mg. to 10grams | 50 mg. to 10 grams |
Vial Size | 5ml to 250ml | 5ml to 250ml |
Filling Accuracy | ± 2 – 3% in single dosing depending upon consistency and uniformity of bulk density of Injectable Powder | ± 2 – 3% in single dosing depending upon consistency and uniformity of bulk density of Injectable Powder |
Power Load | 3.5 H. P. | 4.5 H. P. |
Overall Dimension | 2600mm (L) X 1100mm (W) X 1800mm (H) approx. | 3000mm (L) X 1100mm (W) X 1800mm (H) approx. |
Net Weight | 500 kgs. approx. | 700 kgs. approx. |
Gross Weight | 750 kgs. approx. | 950 kgs. approx. |
* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.
The machine uses a vacuum and air pressure-based powder wheel to dose the exact amount of powder into each vial. A self-picking roller-based system then automatically places sterilized rubber stoppers onto the filled vials. The entire process is mechanically synchronized for smooth, high-speed operation with minimal manual intervention.
Depending on the model and configuration, Dry Powder Filling Bunging Machines can operate at speeds of up to 120 or 250 vials per minute. Actual output varies based on fill volume, powder characteristics, and vial size.
These machines typically deliver high filling accuracy in the range of ±1% to ±2%, depending on powder properties and environmental conditions. The vacuum-pressure dosing system ensures consistent and repeatable fill weights.
All parts that come into contact with the powder, vials, or rubber stoppers are made from stainless steel SS316. The machine frame is also finished in stainless steel and designed to meet cGMP standards, ensuring durability, easy cleaning, and regulatory compliance.
The machine is designed for round glass vials and can handle a variety of free-flowing and semi-free-flowing dry powders used in injectable formulations. Different combinations of filling heads and powder wheels allow flexibility for various fill volumes and production requirements.
Key benefits include high-speed combined filling and bunging, excellent dosing accuracy, reduced powder wastage, compact design that saves cleanroom space, easy operation, and compliance with pharmaceutical quality standards. The integrated process also minimizes contamination risks.
Contact parts are designed for easy removal and are compatible with autoclaving or sterilization processes. The stainless-steel construction and hygienic design support thorough cleaning and help maintain aseptic conditions required in sterile manufacturing.
Yes. Modern models incorporate systems such as “No Vial – No Fill” to prevent powder dosing when a vial is absent, along with other interlocks that stop the machine if rubber stoppers are not properly available. These features significantly reduce product loss and operational errors.
Yes. The machine is available in various combinations of filling heads and powder wheels. This allows manufacturers to configure the system for higher speeds, larger fill volumes, or specific product requirements while maintaining accuracy and reliability.
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Connect with our engineering team to discuss your specific production requirements. We provide customized, cGMP-compliant machinery solutions designed to optimize your manufacturing facility and maximize output.
Adinath International manufactures high-precision pharmaceutical packaging machinery and production plants, providing reliable, hygienic, and efficient solutions for global pharmaceutical industries.
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