Vial Filling Machine

Description

Vial Filling Machine is a technically sophisticated device that accurately fills and dispenses liquid or powder materials. As the name implies, it fills “vials.” These are prefabricated little bottles that are often made of special polymers or borosilicate glass. The open handling of the containers between cleaning and sealing is a crucial step in this process, which is why the strictest environmental hygiene regulations are applicable.

The pharmaceutical sector makes considerable use of vial filling machines to fill vials with pharmaceutical substances. These incredibly robust devices are made to carry out the exact process of quickly filling vials. In order to satisfy the expectations of the pharmaceutical business, vial filling machines also have several filling heads, which allow them achieve a higher filling rate and increased productivity. Vial-filling machines come in a variety of forms that are appropriate for various uses in the pharmaceutical sector.

The main machine, unscrambler, conveyor, stopper feeding bowl, and scrambler make up the vial liquid filling machine. The vials are moved via the conveyor belt to the filling station, where the machine is filled with liquid. Liquids or fluids of different viscosities are filled into vials using vial liquid filling equipment. The pharmaceutical sector makes extensive use of these devices to guarantee accurate vial filling. The liquid filling machine for vials uses the volumetric concept and diving nozzle to deliver sterile and accurate filling operations.

Working Principle of Vial Filling Machine

The incoming dry vials (sterilized and siliconized) are fed through the unscrambler and suitably guided on the moving Delrin slat conveyor belt at the required speed of the correct placement below filling unit.

 

The filling unit consists of Filling Head, Syringes & Nozzles; Syringes & Nozzles are made of AISI SS 316L materials. A Star Wheel is provided which holds the vial during filling operation. A sensor is provided for ”No Vial-No Filling” operation. Syringes are mounted on eccentric block and driving through bottom main gear box. Volume can be increase & decrease by increasing or decreasing stroke length of piston as per filling size. Syringes is having non return valve for sucking and delivering situation to avoid volume variation. Liquid reaches to filling nozzles through silicon transparent pipe. Nozzles having up & down movement with help of cam mechanism, and it come down when vial hold by starwheel for filling operation and starts filling when it starts to move up and after completion of filling operation, starwheel delivers two vials together on conveyor for rubber stoppering operation.

Stoppering unit consist of Star wheel, Vibrator unit and Bowl. The sterilized and siliconized rubber stoppers stored in the vibrator bowl moves vertically to the rubber stopper chute. The vial is hold firmly by starwheel, which will be in continuous rotary motion and vial which is coming from filling unit get in to starwheel and move in rotary direction along with starwheel, during movement it picks up the rubber stopper from the exit end of the chute and rubber stopper pressed by fix single pressing roller, which is spring loaded. Then vial further move on conveyor and collected on out feed starwheel for next sealing operation.

Technical Specification of Vial Filling Machine

Model

ALVF-40

ALVF-80

ALVF-120

ALVF – 250

Filling Heads

Two

Four

Eight

Twelve

Production Rate

Up to 40 Vials/Minute

Up to 80 Vials/Minute

Up to 150 Vials/Minute

Up to 250 Vials/Minute

Input Specification

    

Vial Diameter

15mm to 70mm

15mm to 70mm

15mm to 70mm

15mm to 70mm

Vial Height

25mm to 140mm

25mm to 140mm

25mm to 140mm

25mm to 140mm

  

Filling Precision

±1%

±1%

±1%

±1%

Power Required

1 H.P.

1.5 H.P.

2 H.P.

2 H.P.

Electrical Characteristics

440 Volts, 3 Phase, 50 Hertz

440 Volts, 3 Phase, 50 Hertz

440 Volts, 3 Phase, 50 Hertz

440 Volts, 3 Phase, 50 Hertz

Overall Dimension

2050mm (L) x 850mm (W) x 1700mm (H)

2200mm (L) x 850mm (W) x 1700mm (H)

3000mm (L) x 945mm (W) x 1700mm (H)

3500mm (L) x 945mm (W) x 1700mm (H)

* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.

Types of Vial Filling Machine

Applications of Vial Filling Machine

Advantages of Vial Filling Machine

High Filling Accuracy

High Production Output

Superior Sterility & Reduced Contamination Risk

Significant Reduction in Product Wastage

Easy Changeover & High Flexibility

Key Features & Functions of Vial Filling Machine

  • Filling Technologies: Peristaltic pumps, piston pumps, time-pressure, or mass flow filling for high accuracy

 

  • Stoppering & Capping: Integrated in-line or rotary systems for partial or full rubber stopper insertion and aluminum crimp capping

 

  • Sterility Options:
    • Aseptic filling with isolators/RABS
    • Laminar airflow (LAF) or oRABS
    • Vaporized Hydrogen Peroxide (VHP) decontamination

 

  • Vial Handling: No-glass-to-glass contact, starwheels, puck systems, or robotic handling to prevent breakage and contamination

 

  • Capacity Range: From laboratory-scale to high-speed production lines

 

  • Vial Sizes: Typically 2 ml to 100 ml

 

  • Cleaning & Sterilization: CIP/SIP capable

FAQ for Vial Filling Machine

The machine supports 2 ml to 250 ml fill volumes.

  • Vial Diameter: 15 mm to 70 mm
  • Vial Height: 25 mm to 140 mm

It is suitable for a wide range of round glass vials with quick-change parts for different formats.

The machine provides high filling accuracy of ±0.5% to ±1%. It uses precision piston pumps or peristaltic pumps with SS 316L syringes and non-return valves, ensuring consistent dosing and minimal variation even with different viscosities.

Yes. It is designed for aseptic processing with SS 316L product contact parts, compatibility with laminar airflow (Class 100), and features like “No Vial – No Filling” and minimal open-vial exposure time. Nitrogen flushing (pre & post filling) is available for oxygen-sensitive products.

Major features include:

  • No Vial – No Filling” and “No Vial – Machine Stop” systems
  • Digital vial counter
  • In-feed unscrambler / turn table
  • Diving nozzles with cam mechanism
  • Variable speed control
  • Overload protection
  • Easy-to-clean and autoclavable contact parts

These reduce wastage, prevent spillage, and enhance operator safety.

Countries We Export to

United States | Canada | Mexico | Brazil | Argentina | Chile | Colombia | Peru | Germany | United Kingdom | France | Italy | Spain | Netherlands | Belgium | Switzerland | Sweden | Austria | Denmark | Norway | Poland | Finland | Czech Republic | Hungary | Portugal | Ireland | Greece | Slovakia | Romania | Bulgaria | China | Japan | India | South Korea | Indonesia | Vietnam | Thailand | Malaysia | Philippines | Singapore | Bangladesh | Pakistan | Saudi Arabia | United Arab Emirates | Israel | Turkey | Iran | Qatar | Kuwait | South Africa | Nigeria | Egypt | Algeria | Morocco | Kenya | Ghana | Tunisia | Australia | New Zealand | Russia | Ukraine | Belarus | Kazakhstan | Taiwan | Hong Kong | South Sudan | Uzbekistan | Oman | Jordan | Bahrain | Sri Lanka | Myanmar | Lebanon | Mongolia | Ethiopia | Libya | Angola | Zambia | Zimbabwe | Mozambique | Ivory Coast | Senegal | Uganda | Tanzania | Botswana | Ecuador | Venezuela | Bolivia | Paraguay | Uruguay | Trinidad and Tobago | Panama | Guatemala | Costa Rica | Honduras | El Salvador | Nicaragua | Dominican Republic | Haiti | Cuba

Partner with Industry Experts

Connect with our engineering team to discuss your specific production requirements. We provide customized, cGMP-compliant machinery solutions designed to optimize your manufacturing facility and maximize output.

Adinath International manufactures high-precision vial powder filling machines and complete packaging lines, providing reliable, hygienic, and efficient solutions for global pharmaceutical industries.

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